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ve than PthA2 to inhibit the CsCyp activity. This observation is in line with our prior research around the interaction of CsCyp with RD2 and five.five rep+CT. Given that PthA2 inhibited the CsCyp activity and that CsA disrupted the CsCyp-CTD interaction, we tested regardless of whether CsA could also disrupt the PthA2-CsCyp complicated. Certainly, CsA prevented PthA2 from binding to CsCyp in GSTp
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